|
Polidocanol
has a sclerosant and local anaesthetic effect. This
permits almost painless sclerotherapy. The effect is
directed mostly at the vein intima. While there is great
affinity with damaged intima there is no effect on intact
vascular linings, so a sclerosant effect occurs only on veins
with actual varicose changes and not on veins with moderate
cylindrical dilation.
This sclerosant effect is due to irritation of the vein intima,
which causes a local, adhesive thrombosis in the area of the
damaged endothelium.
The
compression bandage applied after treatment presses the vein
walls together and prevents re-canalization of the organized
thrombus, so that the desired conversion of the thrombus into
a fibrous scar takes place. With paravasal application of
Polidocanol, the local oedema formation leads to compression
of the varices and cicatricial consolidation.
|
|
 |
|
With
appropriate selection of concentration and dosage and with
correct treatment methods and aftercare (compression treatment),
polidocanol can be easily tolerated and is reliable and lasting
sclerosant.
Indication:
Sclerotherapy
of various (branch varicosis; perforantes varicosis; operative
main vein varicosis treatment combined with sclerotherapy),
venectasias (spider veins), haemorrhoids, anal fissures and
gaemangiomas
Dosage
& Administration:
Conventional
Dosage: Polidocanol is for strictly intravenous injection
(sclerotherapy of varices) or strictly sub mucous injection
(sclerotherapy of haemorrhoids). In general, a dose of 2 mg/kg
body weight per day should not be exceeded.
|
