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Aquatech
Several
drugs are sparingly soluble in water. As a result, injectable solutions
of such drugs are prepared using organic solvents like propylene
glycol as co-solvent along with water. Incorporation of propylene
glycol in the formulation causes pain at the site of injection,
which is due to high viscosity of propylene glycol.
For
the first time in the world, Diclofenac 75mg/1ml injection is introduced
for the management of acute pain. Unlike conventional Diclofenac
injections, 1ml Dynapar AQ injection can be given intra-deltoid
as well.
Multicentric
clinical studies have proven the efficacy and safety of 75mg/1ml
Diclofenac injections. Bioequivalence studies show that Dynapar
AQ 1ml injection offers higher bioavailability compared to conventional
3ml Diclofenac injections.
Studies
have shown that majority of intra-gluteal injections may actually
be subcutaneous and it is proven that the rate of absorption is
faster when given intra-deltoid rather than intra-gluteal. Moreover,
it is also known, that smaller volumes of concentrated solution
cause less muscle damage as compared to larger volumes of relatively
less concentrated solution.
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