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Intraoral
Drug Delivery
Intraoral
drug delivery technology provides an excellent route of drug administration
for delivery of drugs into systemic circulation as well as locally
to buccal mucosa.
Intraoral
route provides several advantages such as prompt onset of action
and predictable delivery of drugs. It is especially helpful in drugs
that either undergo extensive first pass metabolism or are destroyed
in the stomach by the content of gastric fluids. However, tissue
permeability of the mucosa, size of the drug molecule and solubility
of the drug provide challenges to Intraoral route of drug delivery.
Both
Buccomax and Vectoral provide platforms to manufacture Intraoral
formulations with prompt onset of action. Furthermore, Vectoral
also enables manufacture of muco-adhesive sustained release formulations.
The Buccomax and Vectoral technology can be beneficially employed
to manufacture various dosage forms of drugs such as analgesics/
antipyretics, anti-spasmodics, anti-emetics, tranquilizers etc.
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