Description:
Myonit
SR - Sustained release tablets are preferred in
long term management of Angina. Due to the matrix
technology, effective concentrations are maintained
for prolonged period of time & adequate nitrate
free period is also maintained. Chances of tolerance
development are less due to this. The principal
pharmacological action of nitroglycerin is relaxation
of vascular smooth muscle.
Nitroglycerin
forms free radical nitric oxide (NO) which activates
guanylate cyclase, resulting in an increase of
guanosine 3'5' monophosphate (cyclic GMP) in smooth
muscle and other tissues.
These events lead to dephosphorylation of myosin
light chains, which regulate the contractile state
in smooth muscle, and result in vasodilatation.
Indication:
Indicated
for the prophylaxis of angina pectoris due to
coronary artery disease.
Brand
Availability:
Brand
Composition
Features
Presentation
Packing
Myonit
SR Tablet
Each
uncoated
tablet contains:
Concentrated
Glyceryl Trinitrate
Solution Equivalent
to Glyceryl Trinitrate 2.6 mg/6.4 mg
(In a controlled release system)
Manufactured
by unique Matrix Technology
Optimum
Nitroglycerin level for extended period of time
