Pre Filled Syringe (PFS)

Innovations: In recent years, various technical innovations were realized and new methods developed, making the use of pre-filled syringe (PFS) and cartridge systems much more convenient and attractive.

Anti-Counterfeiting Measures: Originality seals assure the originality of a product from its manufacture to its use on the patient. PFS offer several advantages over traditional packaging in ampoules/vials. A couple of advantages are ease of use and elimination of several steps that are required before use of a drug in an ampoule/vial. If the drug is lyophilized, one of these steps is reconstitution.

Elimination of dosing errors: PFS contain the exact deliverable dose desired. Vials are overfilled by up to 25%, especially if the desired dose is very small, to ensure that the user may withdraw the desired dose. This overfill of vials allows the possibility of dosing errors that are eliminated with PFS. With PFS it is possible to increase the drug supply and reduce waste. Elimination of the need to overfill reduces wastage of the product and assures delivery of the complete dose.

PFS assures Delivery of particulate free solution: PFS accommodate volumes that typically range from 0.25 to 5.0 ml They are therefore best suited to products administered by subcutaneous or intramuscular injection. Three categories account for the bulk of PFS: anti-thrombotics, vaccines and biotech drugs. PFS are aseptic.

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